RASSF1A promoter methylation and expression analysis in normal and neoplastic kidney indicates a role in early tumorigenesis

BACKGROUND: Epigenetic silencing of the RAS association domain family 1A (RASSF1A) tumor suppressor gene promoter has been demonstrated in renal cell carcinoma (RCC) as a result of promoter hypermethylation. Contradictory results have been reported for RASSF1A methylation in normal kidney, thus it i...

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Detalles Bibliográficos
Autores principales: Peters, Inga, Rehmet, Kristina, Wilke, Nadine, Kuczyk, Markus A, Hennenlotter, Jörg, Eilers, Tyark, Machtens, Stefan, Jonas, Udo, Serth, Jürgen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939711/
https://www.ncbi.nlm.nih.gov/pubmed/17634119
http://dx.doi.org/10.1186/1476-4598-6-49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939711/
https://www.ncbi.nlm.nih.gov/pubmed/17634119
http://dx.doi.org/10.1186/1476-4598-6-49

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