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RASSF1A promoter methylation and expression analysis in normal and neoplastic kidney indicates a role in early tumorigenesis

BACKGROUND: Epigenetic silencing of the RAS association domain family 1A (RASSF1A) tumor suppressor gene promoter has been demonstrated in renal cell carcinoma (RCC) as a result of promoter hypermethylation. Contradictory results have been reported for RASSF1A methylation in normal kidney, thus it i...

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Detalles Bibliográficos
Autores principales:	Peters, Inga, Rehmet, Kristina, Wilke, Nadine, Kuczyk, Markus A, Hennenlotter, Jörg, Eilers, Tyark, Machtens, Stefan, Jonas, Udo, Serth, Jürgen
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939711/ https://www.ncbi.nlm.nih.gov/pubmed/17634119 http://dx.doi.org/10.1186/1476-4598-6-49

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