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Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes

BACKGROUND: Two recombinant, live attenuated human parainfluenza virus type 1 (rHPIV1) mutant viruses have been developed, using a reverse genetics system, for evaluation as potential intranasal vaccine candidates. These rHPIV1 vaccine candidates have two non-temperature sensitive (non-ts) attenuati...

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Detalles Bibliográficos
Autores principales:	Bartlett, Emmalene J, Castaño, Adam, Surman, Sonja R, Collins, Peter L, Skiadopoulos, Mario H, Murphy, Brian R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939843/ https://www.ncbi.nlm.nih.gov/pubmed/17605811 http://dx.doi.org/10.1186/1743-422X-4-67

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