DNA Replication Stress Is a Determinant of Chronological Lifespan in Budding Yeast

The chronological lifespan of eukaryotic organisms is extended by the mutational inactivation of conserved growth-signaling pathways that regulate progression into and through the cell cycle. Here we show that in the budding yeast S. cerevisiae, these and other lifespan-extending conditions, includi...

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Detalles Bibliográficos
Autores principales: Weinberger, Martin, Feng, Li, Paul, Anita, Smith, Daniel L., Hontz, Robert D., Smith, Jeffrey S., Vujcic, Marija, Singh, Keshav K., Huberman, Joel A., Burhans, William C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939877/
https://www.ncbi.nlm.nih.gov/pubmed/17710147
http://dx.doi.org/10.1371/journal.pone.0000748

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