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Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma

Xanthogranulomatous inflammation is a distinguished histopathological entity affecting several organs, predominantly the kidney and gallbladder. So far, only a small number of cases of xanthogranulomatous inflammation occurring in female genital tract have been described, most frequently affecting t...

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Autores principales: Doğan-Ekici, A. Işın, Usubütün, Alp, Küçükali, Türkan, Ayhan, Ali
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939916/
https://www.ncbi.nlm.nih.gov/pubmed/17710239
http://dx.doi.org/10.1155/2007/34763
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author Doğan-Ekici, A. Işın
Usubütün, Alp
Küçükali, Türkan
Ayhan, Ali
author_facet Doğan-Ekici, A. Işın
Usubütün, Alp
Küçükali, Türkan
Ayhan, Ali
author_sort Doğan-Ekici, A. Işın
collection PubMed
description Xanthogranulomatous inflammation is a distinguished histopathological entity affecting several organs, predominantly the kidney and gallbladder. So far, only a small number of cases of xanthogranulomatous inflammation occurring in female genital tract have been described, most frequently affecting the endometrium and histologically characterized by replacement of endometrium by xanthogranulomatous inflammation composed of abundant foamy histiocytes, siderophages, giant cells, fibrosis, calcification and accompanying polymorphonuclear leucocytes, plasma cells and lymphocytes of polyclonal origin. We present a case of a 69-year-old female complained of post menopausal bleeding and weight loss. Clinical preliminary diagnoses were endometrial carcinoma or hyperplasia and ultrasound was supposed to be endometrial malignancy, hyperplasia or pyometra by radiologist. Histopathological examination of uterus revealed xanthogranulomatous endometritis. Since xanthogranulomatous endometritis may mimic endometrial malignancy clinically and pathologically as a result of the replacement of the endometrium and occasionally invasion of the myometrium by friable yellowish tissue composed of histiocytes, knowledge of this unusual inflammatory disease is needed for both clinicians and pathologists.
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spelling pubmed-19399162007-08-20 Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma Doğan-Ekici, A. Işın Usubütün, Alp Küçükali, Türkan Ayhan, Ali Infect Dis Obstet Gynecol Case Report Xanthogranulomatous inflammation is a distinguished histopathological entity affecting several organs, predominantly the kidney and gallbladder. So far, only a small number of cases of xanthogranulomatous inflammation occurring in female genital tract have been described, most frequently affecting the endometrium and histologically characterized by replacement of endometrium by xanthogranulomatous inflammation composed of abundant foamy histiocytes, siderophages, giant cells, fibrosis, calcification and accompanying polymorphonuclear leucocytes, plasma cells and lymphocytes of polyclonal origin. We present a case of a 69-year-old female complained of post menopausal bleeding and weight loss. Clinical preliminary diagnoses were endometrial carcinoma or hyperplasia and ultrasound was supposed to be endometrial malignancy, hyperplasia or pyometra by radiologist. Histopathological examination of uterus revealed xanthogranulomatous endometritis. Since xanthogranulomatous endometritis may mimic endometrial malignancy clinically and pathologically as a result of the replacement of the endometrium and occasionally invasion of the myometrium by friable yellowish tissue composed of histiocytes, knowledge of this unusual inflammatory disease is needed for both clinicians and pathologists. Hindawi Publishing Corporation 2007 2007-06-07 /pmc/articles/PMC1939916/ /pubmed/17710239 http://dx.doi.org/10.1155/2007/34763 Text en Copyright © 2007 A. Işın Doğan-Ekici et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Doğan-Ekici, A. Işın
Usubütün, Alp
Küçükali, Türkan
Ayhan, Ali
Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma
title Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma
title_full Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma
title_fullStr Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma
title_full_unstemmed Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma
title_short Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma
title_sort xanthogranulomatous endometritis: a challenging imitator of endometrial carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939916/
https://www.ncbi.nlm.nih.gov/pubmed/17710239
http://dx.doi.org/10.1155/2007/34763
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