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Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with α4β1 integrins

BACKGROUND: The regeneration of peripheral nerve is associated with a change in the alternative splicing of the fibronectin primary gene transcript to re-express embryonic isoforms containing a binding site for α4β1 integrins that promote neurite outgrowth. Here we use PC12 cells to examine the role...

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Detalles Bibliográficos
Autores principales: Vogelezang, Mariette, Forster, Ulrike B, Han, Jaewon, Ginsberg, Mark H, ffrench-Constant, Charles
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940015/
https://www.ncbi.nlm.nih.gov/pubmed/17603879
http://dx.doi.org/10.1186/1471-2202-8-44