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A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression data
BACKGROUND: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, the regulation process in genetic systems is inherently non-linear in nature, and most studies employ a time-course analysi...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940027/ https://www.ncbi.nlm.nih.gov/pubmed/17603872 http://dx.doi.org/10.1186/1471-2105-8-228 |