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The Relationship between Early Childhood Blood Lead Levels and Performance on End-of-Grade Tests

BACKGROUND: Childhood lead poisoning remains a critical environmental health concern. Low-level lead exposure has been linked to decreased performance on standardized IQ tests for school-aged children. OBJECTIVE: In this study we sought to determine whether blood lead levels in early childhood are r...

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Autores principales: Miranda, Marie Lynn, Kim, Dohyeong, Galeano, M. Alicia Overstreet, Paul, Christopher J., Hull, Andrew P., Morgan, S. Philip
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940087/
https://www.ncbi.nlm.nih.gov/pubmed/17687454
http://dx.doi.org/10.1289/ehp.9994
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author Miranda, Marie Lynn
Kim, Dohyeong
Galeano, M. Alicia Overstreet
Paul, Christopher J.
Hull, Andrew P.
Morgan, S. Philip
author_facet Miranda, Marie Lynn
Kim, Dohyeong
Galeano, M. Alicia Overstreet
Paul, Christopher J.
Hull, Andrew P.
Morgan, S. Philip
author_sort Miranda, Marie Lynn
collection PubMed
description BACKGROUND: Childhood lead poisoning remains a critical environmental health concern. Low-level lead exposure has been linked to decreased performance on standardized IQ tests for school-aged children. OBJECTIVE: In this study we sought to determine whether blood lead levels in early childhood are related to educational achievement in early elementary school as measured by performance on end-of-grade (EOG) testing. METHODS: Educational testing data for 4th-grade students from the 2000–2004 North Carolina Education Research Data Center were linked to blood lead surveillance data for seven counties in North Carolina and then analyzed using exploratory and multivariate statistical methods. RESULTS: The discernible impact of blood lead levels on EOG testing is demonstrated for early childhood blood lead levels as low as 2 μg/dL. A blood lead level of 5 μg/dL is associated with a decline in EOG reading (and mathematics) scores that is roughly equal to 15% (14%) of the interquartile range, and this impact is very significant in comparison with the effects of covariates typically considered profoundly influential on educational outcomes. Early childhood lead exposures appear to have more impact on performance on the reading than on the mathematics portions of the tests. CONCLUSIONS: Our emphasis on population-level analyses of children who are roughly the same age linked to previous (rather than contemporaneous) blood lead levels using achievement (rather than aptitude) outcome complements the important work in this area by previous researchers. Our results suggest that the relationship between blood lead levels and cognitive outcomes are robust across outcome measures and at low levels of lead exposure.
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spelling pubmed-19400872007-08-08 The Relationship between Early Childhood Blood Lead Levels and Performance on End-of-Grade Tests Miranda, Marie Lynn Kim, Dohyeong Galeano, M. Alicia Overstreet Paul, Christopher J. Hull, Andrew P. Morgan, S. Philip Environ Health Perspect Research BACKGROUND: Childhood lead poisoning remains a critical environmental health concern. Low-level lead exposure has been linked to decreased performance on standardized IQ tests for school-aged children. OBJECTIVE: In this study we sought to determine whether blood lead levels in early childhood are related to educational achievement in early elementary school as measured by performance on end-of-grade (EOG) testing. METHODS: Educational testing data for 4th-grade students from the 2000–2004 North Carolina Education Research Data Center were linked to blood lead surveillance data for seven counties in North Carolina and then analyzed using exploratory and multivariate statistical methods. RESULTS: The discernible impact of blood lead levels on EOG testing is demonstrated for early childhood blood lead levels as low as 2 μg/dL. A blood lead level of 5 μg/dL is associated with a decline in EOG reading (and mathematics) scores that is roughly equal to 15% (14%) of the interquartile range, and this impact is very significant in comparison with the effects of covariates typically considered profoundly influential on educational outcomes. Early childhood lead exposures appear to have more impact on performance on the reading than on the mathematics portions of the tests. CONCLUSIONS: Our emphasis on population-level analyses of children who are roughly the same age linked to previous (rather than contemporaneous) blood lead levels using achievement (rather than aptitude) outcome complements the important work in this area by previous researchers. Our results suggest that the relationship between blood lead levels and cognitive outcomes are robust across outcome measures and at low levels of lead exposure. National Institute of Environmental Health Sciences 2007-08 2007-04-27 /pmc/articles/PMC1940087/ /pubmed/17687454 http://dx.doi.org/10.1289/ehp.9994 Text en http://creativecommons.org/publicdomain/mark/1.0/ Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, ?Reproduced with permission from Environmental Health Perspectives?); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.
spellingShingle Research
Miranda, Marie Lynn
Kim, Dohyeong
Galeano, M. Alicia Overstreet
Paul, Christopher J.
Hull, Andrew P.
Morgan, S. Philip
The Relationship between Early Childhood Blood Lead Levels and Performance on End-of-Grade Tests
title The Relationship between Early Childhood Blood Lead Levels and Performance on End-of-Grade Tests
title_full The Relationship between Early Childhood Blood Lead Levels and Performance on End-of-Grade Tests
title_fullStr The Relationship between Early Childhood Blood Lead Levels and Performance on End-of-Grade Tests
title_full_unstemmed The Relationship between Early Childhood Blood Lead Levels and Performance on End-of-Grade Tests
title_short The Relationship between Early Childhood Blood Lead Levels and Performance on End-of-Grade Tests
title_sort relationship between early childhood blood lead levels and performance on end-of-grade tests
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940087/
https://www.ncbi.nlm.nih.gov/pubmed/17687454
http://dx.doi.org/10.1289/ehp.9994
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