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A constrained polynomial regression procedure for estimating the local False Discovery Rate
BACKGROUND: In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which quantifies the evidence of a specific gene association with a clinical or biological variable of interest, is a relevant...
Autores principales: | Dalmasso, Cyril, Bar-Hen, Avner, Broët, Philippe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940264/ https://www.ncbi.nlm.nih.gov/pubmed/17603882 http://dx.doi.org/10.1186/1471-2105-8-229 |
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