Cargando…

Extended Follow-Up Following a Phase 2b Randomized Trial of the Candidate Malaria Vaccines FP9 ME-TRAP and MVA ME-TRAP among Children in Kenya

BACKGROUND: “FFM ME-TRAP” is sequential immunisation with two attenuated poxvirus vectors (FP9 and modified vaccinia virus Ankara) delivering the pre-erythrocytic malaria antigen ME-TRAP. Over nine months follow-up in our original study, there was no evidence that FFM ME-TRAP provided protection aga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bejon, Philip, Ogada, Edna, Mwangi, Tabitha, Milligan, Paul, Lang, Trudie, Fegan, Greg, Gilbert, Sarah C., Peshu, Norbert, Marsh, Kevin, Hill, Adrian V.S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940326/ https://www.ncbi.nlm.nih.gov/pubmed/17710125 http://dx.doi.org/10.1371/journal.pone.0000707

Ejemplares similares

A Phase 2b Randomised Trial of the Candidate Malaria Vaccines FP9 ME-TRAP and MVA ME-TRAP among Children in Kenya
por: Bejon, Philip, et al.
Publicado: (2006)

Immunogenicity of ChAd63 + MVA ME-TRAP in Senegalese adults
por: Mensah, Victorine, et al.
Publicado: (2014)

Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants
por: Afolabi, Muhammed O, et al.
Publicado: (2016)

Humoral immunogenicity of ChAd63_MVA ME-TRAP vaccination in African infants and children
por: Bowyer, Georgina, et al.
Publicado: (2014)

Correction: Interactions between Age and ITN Use Determine the Risk of Febrile Malaria in Children
por: Bejon, Philip, et al.
Publicado: (2011)

Interactions between Age and ITN Use Determine the Risk of Febrile Malaria in Children
por: Bejon, Philip, et al.
Publicado: (2009)

Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults
por: Ogwang, Caroline, et al.
Publicado: (2013)

Clearing asymptomatic parasitaemia increases the specificity of the definition of mild febrile malaria
por: Bejon, Philip, et al.
Publicado: (2007)

A Randomised, Double-Blind, Controlled Vaccine Efficacy Trial of DNA/MVA ME-TRAP Against Malaria Infection in Gambian Adults
por: Moorthy, Vasee S, et al.
Publicado: (2004)

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal
por: Mensah, Victorine A., et al.
Publicado: (2016)

Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya
por: O'Meara, Wendy P, et al.
Publicado: (2008)

First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children
por: Tiono, Alfred B., et al.
Publicado: (2018)

Clearance of Asymptomatic P. falciparum Infections Interacts with the Number of Clones to Predict the Risk of Subsequent Malaria in Kenyan Children
por: Liljander, Anne, et al.
Publicado: (2011)

Injection and trapping of the beam at 800 MeV in the CPS
por: Boussard, D, et al.
Publicado: (1974)

Injection and trapping of the beam at 800 MeV in the CPS
por: Boussard, Daniel, et al.
Publicado: (1974)

The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS
por: Kashi, Alex A., et al.
Publicado: (2019)

Defining Childhood Severe Falciparum Malaria for Intervention Studies
por: Bejon, Philip, et al.
Publicado: (2007)

Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals
por: Hodgson, Susanne H., et al.
Publicado: (2015)

Defining Clinical Malaria: The Specificity and Incidence of Endpoints from Active and Passive Surveillance of Children in Rural Kenya
por: Olotu, Ally, et al.
Publicado: (2010)

Correction: Defining Clinical Malaria: The Specificity and Incidence of Endpoints from Active and Passive Surveillance of Children in Rural Kenya
por: Olotu, Ally, et al.
Publicado: (2011)

Helminth Infection and Eosinophilia and the Risk of Plasmodium falciparum Malaria in 1- to 6-Year-Old Children in a Malaria Endemic Area
por: Bejon, Philip, et al.
Publicado: (2008)

Identifying children with excess malaria episodes after adjusting for variation in exposure: identification from a longitudinal study using statistical count models
por: Ndungu, Francis Maina, et al.
Publicado: (2015)

Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP
por: Rampling, Tommy, et al.
Publicado: (2018)

ClassifyMe: A Field-Scouting Software for the Identification of Wildlife in Camera Trap Images
por: Falzon, Greg, et al.
Publicado: (2019)

Correlation of Memory T Cell Responses against TRAP with Protection from Clinical Malaria, and CD4(+) CD25(high) T Cells with Susceptibility in Kenyans
por: Todryk, Stephen M., et al.
Publicado: (2008)

A novel Plasmodium vivax vaccine based on recombinant chimpanzee adenovirus ChAd63 and MVA expressing TRAP
por: Bauza, Karolis, et al.
Publicado: (2012)

Correction: Correlation of Memory T Cell Responses against TRAP with Protection from Clinical Malaria, and CD4(+) CD25(high) T Cells with Susceptibility in Kenyans
por: Todryk, Stephen M., et al.
Publicado: (2011)

Catch me if you can! Oxidative protein trapping in the intermembrane space of mitochondria
por: Herrmann, Johannes M., et al.
Publicado: (2007)

Impact of exposure to malaria and nutritional status on responses to the experimental malaria vaccine ChAd63 MVA ME-TRAP in 5-17 month-old children in Burkina Faso
por: Morter, Richard, et al.
Publicado: (2022)

Estimating Individual Exposure to Malaria Using Local Prevalence of Malaria Infection in the Field
por: Olotu, Ally, et al.
Publicado: (2012)

The System Is upon Me
por: Milligan, Spike, et al.
Publicado: (1972)

Fraction of all hospital admissions and deaths attributable to malnutrition among children in rural Kenya
por: Bejon, Philip, et al.
Publicado: (2008)

Fast extraction in the M1 line for PS205-HELIUM TRAP at 105 MeV/c
por: Giovannozzi, M, et al.
Publicado: (1996)

Stable and Unstable Malaria Hotspots in Longitudinal Cohort Studies in Kenya
por: Bejon, Philip, et al.
Publicado: (2010)

Correction: Stable and Unstable Malaria Hotspots in Longitudinal Cohort Studies in Kenya
por: Bejon, Philip, et al.
Publicado: (2011)

Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP
por: Bliss, Carly M., et al.
Publicado: (2018)

Inhibition of FGF/FGFR autocrine signaling in mesothelioma with the FGF ligand trap, FP-1039/GSK3052230
por: Blackwell, Christina, et al.
Publicado: (2016)

Experience of using an open source clinical trials data management software system in Kenya
por: Ngari, Moses M, et al.
Publicado: (2014)

Safety and immunogenicity of an FP9-vectored candidate tuberculosis vaccine (FP85A), alone and with candidate vaccine MVA85A in BCG-vaccinated healthy adults: A phase I clinical trial
por: Rowland, Rosalind, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_6bhue3pteaud07vfh4ifdistq2