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Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages

Shigella infection, the cause of bacillary dysentery, induces caspase-1 activation and cell death in macrophages, but the precise mechanisms of this activation remain poorly understood. We demonstrate here that caspase-1 activation and IL-1β processing induced by Shigella are mediated through Ipaf,...

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Detalles Bibliográficos
Autores principales:	Suzuki, Toshihiko, Franchi, Luigi, Toma, Claudia, Ashida, Hiroshi, Ogawa, Michinaga, Yoshikawa, Yuko, Mimuro, Hitomi, Inohara, Naohiro, Sasakawa, Chihiro, Nuñez, Gabriel
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941748/ https://www.ncbi.nlm.nih.gov/pubmed/17696608 http://dx.doi.org/10.1371/journal.ppat.0030111

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