A Screen for Suppressors of Gross Chromosomal Rearrangements Identifies a Conserved Role for PLP in Preventing DNA Lesions

Genome instability is a hallmark of cancer cells. One class of genome aberrations prevalent in tumor cells is termed gross chromosomal rearrangements (GCRs). GCRs comprise chromosome translocations, amplifications, inversions, deletion of whole chromosome arms, and interstitial deletions. Here, we r...

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Detalles Bibliográficos
Autores principales: Kanellis, Pamela, Gagliardi, Mark, Banath, Judit P, Szilard, Rachel K, Nakada, Shinichiro, Galicia, Sarah, Sweeney, Frederic D, Cabelof, Diane C, Olive, Peggy L, Durocher, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941753/
https://www.ncbi.nlm.nih.gov/pubmed/17696614
http://dx.doi.org/10.1371/journal.pgen.0030134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941753/
https://www.ncbi.nlm.nih.gov/pubmed/17696614
http://dx.doi.org/10.1371/journal.pgen.0030134

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