Utrophin Up-Regulation by an Artificial Transcription Factor in Transgenic Mice

Duchenne Muscular Dystrophy (DMD) is a severe muscle degenerative disease, due to absence of dystrophin. There is currently no effective treatment for DMD. Our aim is to up-regulate the expression level of the dystrophin related gene utrophin in DMD, complementing in this way the lack of dystrophin...

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Detalles Bibliográficos
Autores principales: Mattei, Elisabetta, Corbi, Nicoletta, Di Certo, Maria Grazia, Strimpakos, Georgios, Severini, Cinzia, Onori, Annalisa, Desantis, Agata, Libri, Valentina, Buontempo, Serena, Floridi, Aristide, Fanciulli, Maurizio, Baban, Dilair, Davies, Kay E., Passananti, Claudio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942121/
https://www.ncbi.nlm.nih.gov/pubmed/17712422
http://dx.doi.org/10.1371/journal.pone.0000774

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