Founder mutations in BRCA1/2 are not frequent in Canadian Ashkenazi Jewish men with prostate cancer

BACKGROUND: Relatives of BRCA1 and BRCA2 mutation carriers have long been proposed by epidemiological studies to have an increased risk of developing prostate cancer. In the Ashkenazi Jewish (AJ) population, the existence of 3 frequent founder mutations, 185delAG and 5382insC in BRCA1 and 6174delT i...

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Detalles Bibliográficos
Autores principales: Hamel, Nancy, Kotar, Kimberley, Foulkes, William D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194219/
https://www.ncbi.nlm.nih.gov/pubmed/12911837
http://dx.doi.org/10.1186/1471-2350-4-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194219/
https://www.ncbi.nlm.nih.gov/pubmed/12911837
http://dx.doi.org/10.1186/1471-2350-4-7

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