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Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation

Activation of Myc induces epidermal stem cells to exit their niche and differentiate into sebocytes and interfollicular epidermis, a process that is associated with widespread changes in gene transcription. We have identified chromatin modifications that are characteristic of epidermal stem cells an...

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Detalles Bibliográficos
Autores principales: Frye, Michaela, Fisher, Amanda G., Watt, Fiona M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945016/
https://www.ncbi.nlm.nih.gov/pubmed/17712411
http://dx.doi.org/10.1371/journal.pone.0000763