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Strategies to reduce clinical inertia in hypertensive kidney transplant recipients

BACKGROUND: Many kidney transplant recipients have hypertension. Elevated systolic blood pressures are associated with lower patient and kidney allograft survival. METHODS: This retrospective analysis examined the prevalence of clinical inertia (failure to initiate or increase therapy) in the treatm...

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Autores principales: Kiberd, James, Panek, Romauld, Kiberd, Bryce
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945020/
https://www.ncbi.nlm.nih.gov/pubmed/17662139
http://dx.doi.org/10.1186/1471-2369-8-10
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author Kiberd, James
Panek, Romauld
Kiberd, Bryce
author_facet Kiberd, James
Panek, Romauld
Kiberd, Bryce
author_sort Kiberd, James
collection PubMed
description BACKGROUND: Many kidney transplant recipients have hypertension. Elevated systolic blood pressures are associated with lower patient and kidney allograft survival. METHODS: This retrospective analysis examined the prevalence of clinical inertia (failure to initiate or increase therapy) in the treatment of hypertension before and after the introduction of an automated device (BpTRU) in the kidney transplant clinic. RESULTS: Historically only 36% (49/134) of patients were prescribed a change in therapy despite a systolic blood pressure ≥ 130 mmHg. After the introduction of BpTRU, 56% (62/110) of the patients had a change in therapy. In a multivariate logistic regression analysis of the entire cohort (n = 244) therapeutic changes were associated with higher blood pressures (OR 1.08 per mmHg, 95% CI 1.04–1.12) and use of the BpTRU (OR 2.12, 95% CI 1.72–3.83). In addition patients on more medications were also more likely to have a change in therapy. CONCLUSION: Blood pressure measurement with automated devices may help reduce clinical inertia in the kidney transplant clinic.
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spelling pubmed-19450202007-08-11 Strategies to reduce clinical inertia in hypertensive kidney transplant recipients Kiberd, James Panek, Romauld Kiberd, Bryce BMC Nephrol Research Article BACKGROUND: Many kidney transplant recipients have hypertension. Elevated systolic blood pressures are associated with lower patient and kidney allograft survival. METHODS: This retrospective analysis examined the prevalence of clinical inertia (failure to initiate or increase therapy) in the treatment of hypertension before and after the introduction of an automated device (BpTRU) in the kidney transplant clinic. RESULTS: Historically only 36% (49/134) of patients were prescribed a change in therapy despite a systolic blood pressure ≥ 130 mmHg. After the introduction of BpTRU, 56% (62/110) of the patients had a change in therapy. In a multivariate logistic regression analysis of the entire cohort (n = 244) therapeutic changes were associated with higher blood pressures (OR 1.08 per mmHg, 95% CI 1.04–1.12) and use of the BpTRU (OR 2.12, 95% CI 1.72–3.83). In addition patients on more medications were also more likely to have a change in therapy. CONCLUSION: Blood pressure measurement with automated devices may help reduce clinical inertia in the kidney transplant clinic. BioMed Central 2007-07-27 /pmc/articles/PMC1945020/ /pubmed/17662139 http://dx.doi.org/10.1186/1471-2369-8-10 Text en Copyright © 2007 Kiberd et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kiberd, James
Panek, Romauld
Kiberd, Bryce
Strategies to reduce clinical inertia in hypertensive kidney transplant recipients
title Strategies to reduce clinical inertia in hypertensive kidney transplant recipients
title_full Strategies to reduce clinical inertia in hypertensive kidney transplant recipients
title_fullStr Strategies to reduce clinical inertia in hypertensive kidney transplant recipients
title_full_unstemmed Strategies to reduce clinical inertia in hypertensive kidney transplant recipients
title_short Strategies to reduce clinical inertia in hypertensive kidney transplant recipients
title_sort strategies to reduce clinical inertia in hypertensive kidney transplant recipients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945020/
https://www.ncbi.nlm.nih.gov/pubmed/17662139
http://dx.doi.org/10.1186/1471-2369-8-10
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