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Resequencing PNMT in European hypertensive and normotensive individuals: no common susceptibilily variants for hypertension and purifying selection on intron 1

BACKGROUND: Human linkage and animal QTL studies have indicated the contribution of genes on Chr17 into blood pressure regulation. One candidate gene is PNMT, coding for phenylethanolamine-N-methyltransferase, catalyzing the synthesis of epinephrine from norepinephrine. METHODS: Fine-scale variation...

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Detalles Bibliográficos
Autores principales:	Kepp, Katrin, Juhanson, Peeter, Kozich, Viktor, Ots, Mai, Viigimaa, Margus, Laan, Maris
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1947951/ https://www.ncbi.nlm.nih.gov/pubmed/17645789 http://dx.doi.org/10.1186/1471-2350-8-47

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