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Morphine induces endocytosis of neuronal μ-opioid receptors through the sustained transfer of Gα subunits to RGSZ2 proteins

BACKGROUND: In general, opioids that induce the recycling of μ-opioid receptors (MORs) promote little desensitization, although morphine is one exception to this rule. While morphine fails to provoke significant internalization of MORs in cultured cells, it does stimulate profound desensitization. I...

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Detalles Bibliográficos
Autores principales:	Rodríguez-Muñoz, María, de la Torre-Madrid, Elena, Sánchez-Blázquez, Pilar, Garzón, Javier
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1947952/ https://www.ncbi.nlm.nih.gov/pubmed/17634133 http://dx.doi.org/10.1186/1744-8069-3-19

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