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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy

BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common hematological malignancy affecting children. Despite significant progress and success in the treatment of ALL, a significant number of children continue to relapse and for them, outcome remains poor. Therefore, the search for novel th...

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Detalles Bibliográficos
Autores principales:	Sengupta, Tapas K, Leclerc, Gilles M, Hsieh-Kinser, Ting Ting, Leclerc, Guy J, Singh, Inderjit, Barredo, Julio C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1948012/ https://www.ncbi.nlm.nih.gov/pubmed/17623090 http://dx.doi.org/10.1186/1476-4598-6-46

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