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Epithelial Na, K-ATPase expression is down-regulated in canine prostate cancer; a possible consequence of metabolic transformation in the process of prostate malignancy

BACKGROUND: An important physiological function of the normal prostate gland is the synthesis and secretion of a citrate rich prostatic fluid. In prostate cancer, citrate production levels are reduced as a result of altered cellular metabolism and bioenergetics. Na, K-ATPase is essential for citrate...

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Detalles Bibliográficos
Autores principales: Mobasheri, Ali, Fox, Richard, Evans, Iain, Cullingham, Fay, Martín-Vasallo, Pablo, Foster, Christopher S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194866/
https://www.ncbi.nlm.nih.gov/pubmed/12848899
http://dx.doi.org/10.1186/1475-2867-3-8