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Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study

BACKGROUND: Physical activity has long been associated with reduced risk of coronary heart disease (CHD). In this work we evaluated the effect of physical activity on lipid levels, in a sample of cardiovascular disease free people. METHODS: The ATTICA study is a population – based cohort that has ra...

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Autores principales: Skoumas, John, Pitsavos, Christos, Panagiotakos, Demosthenes B, Chrysohoou, Christina, Zeimbekis, Akis, Papaioannou, Ioanna, Toutouza, Marina, Toutouzas, Pavlos, Stefanadis, Christodoulos
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194868/
https://www.ncbi.nlm.nih.gov/pubmed/12852790
http://dx.doi.org/10.1186/1476-511X-2-3
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author Skoumas, John
Pitsavos, Christos
Panagiotakos, Demosthenes B
Chrysohoou, Christina
Zeimbekis, Akis
Papaioannou, Ioanna
Toutouza, Marina
Toutouzas, Pavlos
Stefanadis, Christodoulos
author_facet Skoumas, John
Pitsavos, Christos
Panagiotakos, Demosthenes B
Chrysohoou, Christina
Zeimbekis, Akis
Papaioannou, Ioanna
Toutouza, Marina
Toutouzas, Pavlos
Stefanadis, Christodoulos
author_sort Skoumas, John
collection PubMed
description BACKGROUND: Physical activity has long been associated with reduced risk of coronary heart disease (CHD). In this work we evaluated the effect of physical activity on lipid levels, in a sample of cardiovascular disease free people. METHODS: The ATTICA study is a population – based cohort that has randomly enrolled 2772 individuals, stratified by age – gender (according to the census 2001), from the greater area of Athens, during 2001–2002. Of them, 1376 were men (45 ± 12 years old, range: 18 – 86) and 1396 women (45 ± 13 years old, range: 18 – 88). We assessed the relationship between physical activity status (measured in kcal/min expended per day) and several lipids, after taking into account the effect of several characteristics of the participants. RESULTS: 578 (42%) men and 584 (40%) women were classified as physically active. Compared to sedentary physically active women had significantly lower levels of total serum cholesterol (p < 0.05), LDL (p < 0.05) and oxidized LDL cholesterol (p < 0.05), triglycerides (p < 0.05), apolipoprotein B (p < 0.05), and higher levels of HDL cholesterol (p < 0.05) and apolipoprotein A1 (p < 0.05). Similar associations were observed in men, but the benefits did not reach statistical significance. However, when we adjusted for age, smoking habits and body mass index, physical activity was only significantly associated with higher HDL-cholesterol (p < 0.05) and apolipoprotein A1 (p < 0.05) levels, in women, but not in men. CONCLUSIONS: Substantial independent increases in HDL-cholesterol and apolipoprotein A1 concentrations were observed in women, but not in men, in a Mediterranean cohort.
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spelling pubmed-1948682003-09-16 Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study Skoumas, John Pitsavos, Christos Panagiotakos, Demosthenes B Chrysohoou, Christina Zeimbekis, Akis Papaioannou, Ioanna Toutouza, Marina Toutouzas, Pavlos Stefanadis, Christodoulos Lipids Health Dis Research BACKGROUND: Physical activity has long been associated with reduced risk of coronary heart disease (CHD). In this work we evaluated the effect of physical activity on lipid levels, in a sample of cardiovascular disease free people. METHODS: The ATTICA study is a population – based cohort that has randomly enrolled 2772 individuals, stratified by age – gender (according to the census 2001), from the greater area of Athens, during 2001–2002. Of them, 1376 were men (45 ± 12 years old, range: 18 – 86) and 1396 women (45 ± 13 years old, range: 18 – 88). We assessed the relationship between physical activity status (measured in kcal/min expended per day) and several lipids, after taking into account the effect of several characteristics of the participants. RESULTS: 578 (42%) men and 584 (40%) women were classified as physically active. Compared to sedentary physically active women had significantly lower levels of total serum cholesterol (p < 0.05), LDL (p < 0.05) and oxidized LDL cholesterol (p < 0.05), triglycerides (p < 0.05), apolipoprotein B (p < 0.05), and higher levels of HDL cholesterol (p < 0.05) and apolipoprotein A1 (p < 0.05). Similar associations were observed in men, but the benefits did not reach statistical significance. However, when we adjusted for age, smoking habits and body mass index, physical activity was only significantly associated with higher HDL-cholesterol (p < 0.05) and apolipoprotein A1 (p < 0.05) levels, in women, but not in men. CONCLUSIONS: Substantial independent increases in HDL-cholesterol and apolipoprotein A1 concentrations were observed in women, but not in men, in a Mediterranean cohort. BioMed Central 2003-06-12 /pmc/articles/PMC194868/ /pubmed/12852790 http://dx.doi.org/10.1186/1476-511X-2-3 Text en Copyright © 2003 Skoumas et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
spellingShingle Research
Skoumas, John
Pitsavos, Christos
Panagiotakos, Demosthenes B
Chrysohoou, Christina
Zeimbekis, Akis
Papaioannou, Ioanna
Toutouza, Marina
Toutouzas, Pavlos
Stefanadis, Christodoulos
Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study
title Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study
title_full Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study
title_fullStr Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study
title_full_unstemmed Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study
title_short Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study
title_sort physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the attica study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194868/
https://www.ncbi.nlm.nih.gov/pubmed/12852790
http://dx.doi.org/10.1186/1476-511X-2-3
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