Molecular purging of multiple myeloma cells by ex-vivo culture and retroviral transduction of mobilized-blood CD34(+ )cells

BACKGROUND: Tumor cell contamination of the apheresis in multiple myeloma is likely to affect disease-free and overall survival after autografting. OBJECTIVE: To purge myeloma aphereses from tumor contaminants with a novel culture-based purging method. METHODS: We cultured myeloma-positive CD34(+ )P...

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Detalles Bibliográficos
Autores principales: Deola, Sara, Scaramuzza, Samantha, Birolo, Roberto Sciarretta, Cergnul, Massimiliano, Ficara, Francesca, Dando, Jonathan, Voena, Claudia, Vai, Sergio, Monari, Marta, Pogliani, Enrico, Corneo, Gianmarco, Peccatori, Jacopo, Selleri, Silvia, Bordignon, Claudio, Roncarolo, Maria Grazia, Aiuti, Alessandro, Bregni, Marco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1948885/
https://www.ncbi.nlm.nih.gov/pubmed/17626627
http://dx.doi.org/10.1186/1479-5876-5-35

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