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Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice

BACKGROUND: Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of Alzheimer's disease (AD). We and others have shown that certain NSAIDs reduce secretion of Aβ42 in cell culture and animal models, and that the effect of NSAIDs on Aβ42 is indep...

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Detalles Bibliográficos
Autores principales:	Kukar, Thomas, Prescott, Sonya, Eriksen, Jason L, Holloway, Vallie, Murphy, M Paul, Koo, Edward H, Golde, Todd E, Nicolle, Michelle M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1948891/ https://www.ncbi.nlm.nih.gov/pubmed/17650315 http://dx.doi.org/10.1186/1471-2202-8-54

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