Cargando…

Small but versatile: the extraordinary functional and structural diversity of the β-grasp fold

BACKGROUND: The β-grasp fold (β-GF), prototyped by ubiquitin (UB), has been recruited for a strikingly diverse range of biochemical functions. These functions include providing a scaffold for different enzymatic active sites (e.g. NUDIX phosphohydrolases) and iron-sulfur clusters, RNA-soluble-ligand...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burroughs, A Maxwell, Balaji, S, Iyer, Lakshminarayan M, Aravind, L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949818/ https://www.ncbi.nlm.nih.gov/pubmed/17605815 http://dx.doi.org/10.1186/1745-6150-2-18

Ejemplares similares

A novel superfamily containing the β-grasp fold involved in binding diverse soluble ligands
por: Burroughs, A Maxwell, et al.
Publicado: (2007)

The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like β-grasp domains
por: Iyer, Lakshminarayan M, et al.
Publicado: (2006)

Two novel PIWI families: roles in inter-genomic conflicts in bacteria and Mediator-dependent modulation of transcription in eukaryotes
por: Burroughs, A Maxwell, et al.
Publicado: (2013)

Functional Innovation in the Evolution of the Calcium-Dependent System of the Eukaryotic Endoplasmic Reticulum
por: Schäffer, Daniel E., et al.
Publicado: (2020)

Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts
por: M. Iyer, Lakshminarayan, et al.
Publicado: (2021)

Extraordinary phylogenetic diversity and metabolic versatility in aquifer sediment
por: Castelle, Cindy J., et al.
Publicado: (2013)

Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA
por: Iyer, Lakshminarayan M., et al.
Publicado: (2013)

Unexpected Evolution of Lesion-Recognition Modules in Eukaryotic NER and Kinetoplast DNA Dynamics Proteins from Bacterial Mobile Elements
por: Krishnan, Arunkumar, et al.
Publicado: (2018)

Highly regulated, diversifying NTP-dependent biological conflict systems with implications for the emergence of multicellularity
por: Kaur, Gurmeet, et al.
Publicado: (2020)

Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans
por: Kaur, Gurmeet, et al.
Publicado: (2021)

Apprehending the NAD(+)–ADPr-Dependent Systems in the Virus World
por: Iyer, Lakshminarayan M., et al.
Publicado: (2022)

Unraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitination
por: Iyer, Lakshminarayan M, et al.
Publicado: (2008)

The RAGNYA fold: a novel fold with multiple topological variants found in functionally diverse nucleic acid, nucleotide and peptide-binding proteins
por: Balaji, S., et al.
Publicado: (2007)

The eukaryotic translation initiation regulator CDC123 defines a divergent clade of ATP-grasp enzymes with a predicted role in novel protein modifications
por: Burroughs, A Maxwell, et al.
Publicado: (2015)

Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling
por: Burroughs, A. Maxwell, et al.
Publicado: (2015)

Transposons to toxins: the provenance, architecture and diversification of a widespread class of eukaryotic effectors
por: Zhang, Dapeng, et al.
Publicado: (2016)

Polyvalent Proteins, a Pervasive Theme in the Intergenomic Biological Conflicts of Bacteriophages and Conjugative Elements
por: Iyer, Lakshminarayan M., et al.
Publicado: (2017)

Presence of a classical RRM-fold palm domain in Thg1-type 3'- 5'nucleic acid polymerases and the origin of the GGDEF and CRISPR polymerase domains
por: Anantharaman, Vivek, et al.
Publicado: (2010)

A highly conserved family of domains related to the DNA-glycosylase fold helps predict multiple novel pathways for RNA modifications
por: Burroughs, A Maxwell, et al.
Publicado: (2014)

Reconstructing the ubiquitin network - cross-talk with other systems and identification of novel functions
por: Venancio, Thiago M, et al.
Publicado: (2009)

HPC2 and ubinuclein define a novel family of histone chaperones conserved throughout eukaryotes
por: Balaji, S., et al.
Publicado: (2009)

Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems
por: Iyer, Lakshminarayan M., et al.
Publicado: (2011)

RNA damage in biological conflicts and the diversity of responding RNA repair systems
por: Burroughs, A. Maxwell, et al.
Publicado: (2016)

Detection of novel members, structure–function analysis and evolutionary classification of the 2H phosphoesterase superfamily
por: Mazumder, Raja, et al.
Publicado: (2002)

The natural history of the WRKY–GCM1 zinc fingers and the relationship between transcription factors and transposons
por: Babu, M. Madan, et al.
Publicado: (2006)

Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains
por: Balaji, S., et al.
Publicado: (2005)

Classification and evolutionary history of the single-strand annealing proteins, RecT, Redβ, ERF and RAD52
por: Iyer, Lakshminarayan M, et al.
Publicado: (2002)

The two faces of Alba: the evolutionary connection between proteins participating in chromatin structure and RNA metabolism
por: Aravind, L, et al.
Publicado: (2003)

GRASPs in Golgi Structure and Function
por: Zhang, Xiaoyan, et al.
Publicado: (2016)

Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification
por: Iyer, Lakshminarayan M., et al.
Publicado: (2015)

The Anabaena sensory rhodopsin transducer defines a novel superfamily of prokaryotic small-molecule binding domains
por: De Souza, Robson F, et al.
Publicado: (2009)

An Extraordinary Case of Small-Pox
por: Purton, Thomas
Publicado: (1801)

Discovery of Novel DENN Proteins: Implications for the Evolution of Eukaryotic Intracellular Membrane Structures and Human Disease
por: Zhang, Dapeng, et al.
Publicado: (2012)

The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities
por: Aravind, L, et al.
Publicado: (2002)

The catalytic domains of thiamine triphosphatase and CyaB-like adenylyl cyclase define a novel superfamily of domains that bind organic phosphates
por: Iyer, Lakshminarayan M, et al.
Publicado: (2002)

ALOG domains: provenance of plant homeotic and developmental regulators from the DNA-binding domain of a novel class of DIRS1-type retroposons
por: Iyer, Lakshminarayan M, et al.
Publicado: (2012)

Small subunit ribosomal metabarcoding reveals extraordinary trypanosomatid diversity in Brazilian bats
por: Dario, Maria Augusta, et al.
Publicado: (2017)

Melanin‐Like Nanomaterials for Advanced Biomedical Applications: A Versatile Platform with Extraordinary Promise
por: Liu, Heng, et al.
Publicado: (2020)

An Extraordinary Issue for Extraordinary Times
por: Sammons, Morgan T.
Publicado: (2020)

Knockout of the Golgi stacking proteins GRASP55 and GRASP65 impairs Golgi structure and function
por: Bekier, Michael E., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_naqndelm9fbi21bv2fv5ktk9un