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On State-Space Reduction in Multi-Strain Pathogen Models, with an Application to Antigenic Drift in Influenza A
Many pathogens exist in phenotypically distinct strains that interact with each other through competition for hosts. General models that describe such multi-strain systems are extremely difficult to analyze because their state spaces are enormously large. Reduced models have been proposed, but so fa...
Autores principales: | Kryazhimskiy, Sergey, Dieckmann, Ulf, Levin, Simon A, Dushoff, Jonathan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949840/ https://www.ncbi.nlm.nih.gov/pubmed/17708677 http://dx.doi.org/10.1371/journal.pcbi.0030159 |
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