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Wide-Scale Analysis of Human Functional Transcription Factor Binding Reveals a Strong Bias towards the Transcription Start Site

BACKGROUND: Transcription factors (TF) regulate expression by binding to specific DNA sequences. A binding event is functional when it affects gene expression. Functionality of a binding site is reflected in conservation of the binding sequence during evolution and in over represented binding in gen...

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Detalles Bibliográficos
Autores principales:	Tabach, Yuval, Brosh, Ran, Buganim, Yossi, Reiner, Anat, Zuk, Or, Yitzhaky, Assif, Koudritsky, Mark, Rotter, Varda, Domany, Eytan
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950076/ https://www.ncbi.nlm.nih.gov/pubmed/17726537 http://dx.doi.org/10.1371/journal.pone.0000807

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