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Desensitization and binding properties determine distinct α1β2γ2 and α3β2γ2 GABA(A) receptor-channel kinetic behavior
GABA(A) receptor subtypes comprising the α1 and α3 subunits change with development and have a specific anatomical localization in the adult brain. These receptor subtypes have been previously demonstrated to greatly differ in deactivation kinetics but the underlying gating mechanisms have not been...
Autores principales: | Barberis, Andrea, Mozrzymas, Jerzy W, Ortinski, Pavel I, Vicini, Stefano |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950087/ https://www.ncbi.nlm.nih.gov/pubmed/17561840 http://dx.doi.org/10.1111/j.1460-9568.2007.05530.x |
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