Maintenance of Paternal Methylation and Repression of the Imprinted H19 Gene Requires MBD3

Paternal repression of the imprinted H19 gene is mediated by a differentially methylated domain (DMD) that is essential to imprinting of both H19 and the linked and oppositely imprinted Igf2 gene. The mechanisms by which paternal-specific methylation of the DMD survive the period of genome-wide deme...

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Detalles Bibliográficos
Autores principales: Reese, Kimberly J, Lin, Shu, Verona, Raluca I, Schultz, Richard M, Bartolomei, Marisa S
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950162/
https://www.ncbi.nlm.nih.gov/pubmed/17708683
http://dx.doi.org/10.1371/journal.pgen.0030137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950162/
https://www.ncbi.nlm.nih.gov/pubmed/17708683
http://dx.doi.org/10.1371/journal.pgen.0030137

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