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Maintenance of Paternal Methylation and Repression of the Imprinted H19 Gene Requires MBD3
Paternal repression of the imprinted H19 gene is mediated by a differentially methylated domain (DMD) that is essential to imprinting of both H19 and the linked and oppositely imprinted Igf2 gene. The mechanisms by which paternal-specific methylation of the DMD survive the period of genome-wide deme...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950162/ https://www.ncbi.nlm.nih.gov/pubmed/17708683 http://dx.doi.org/10.1371/journal.pgen.0030137 |