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Kidney Modelling for FDG Excretion with PET
The purpose of this study was to detect the physiological process of FDG's filtration from blood to urine and to establish a mathematical model to describe the process. Dynamic positron emission tomography scan for FDG was performed on seven normal volunteers. The filtration process in kidney c...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950229/ https://www.ncbi.nlm.nih.gov/pubmed/17728841 http://dx.doi.org/10.1155/2007/63234 |
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author | Qiao, Huiting Bai, Jing Chen, Yingmao Tian, Jiahe |
author_facet | Qiao, Huiting Bai, Jing Chen, Yingmao Tian, Jiahe |
author_sort | Qiao, Huiting |
collection | PubMed |
description | The purpose of this study was to detect the physiological process of FDG's filtration from blood to urine and to establish a mathematical model to describe the process. Dynamic positron emission tomography scan for FDG was performed on seven normal volunteers. The filtration process in kidney can be seen in the sequential images of each study. Variational distribution of FDG in kidney can be detected in dynamic data. According to the structure and function, kidney is divided into parenchyma and pelvis. A unidirectional three-compartment model is proposed to describe the renal function in FDG excretion. The time-activity curves that were picked up from the parenchyma, pelvis, and abdominal aorta were used to estimate the parameter of the model. The output of the model has fitted well with the original curve from dynamic data. |
format | Text |
id | pubmed-1950229 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-19502292007-08-29 Kidney Modelling for FDG Excretion with PET Qiao, Huiting Bai, Jing Chen, Yingmao Tian, Jiahe Int J Biomed Imaging Research Article The purpose of this study was to detect the physiological process of FDG's filtration from blood to urine and to establish a mathematical model to describe the process. Dynamic positron emission tomography scan for FDG was performed on seven normal volunteers. The filtration process in kidney can be seen in the sequential images of each study. Variational distribution of FDG in kidney can be detected in dynamic data. According to the structure and function, kidney is divided into parenchyma and pelvis. A unidirectional three-compartment model is proposed to describe the renal function in FDG excretion. The time-activity curves that were picked up from the parenchyma, pelvis, and abdominal aorta were used to estimate the parameter of the model. The output of the model has fitted well with the original curve from dynamic data. Hindawi Publishing Corporation 2007 2007-07-02 /pmc/articles/PMC1950229/ /pubmed/17728841 http://dx.doi.org/10.1155/2007/63234 Text en Copyright © 2007 Huiting Qiao et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Qiao, Huiting Bai, Jing Chen, Yingmao Tian, Jiahe Kidney Modelling for FDG Excretion with PET |
title | Kidney Modelling for FDG Excretion with PET |
title_full | Kidney Modelling for FDG Excretion with PET |
title_fullStr | Kidney Modelling for FDG Excretion with PET |
title_full_unstemmed | Kidney Modelling for FDG Excretion with PET |
title_short | Kidney Modelling for FDG Excretion with PET |
title_sort | kidney modelling for fdg excretion with pet |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950229/ https://www.ncbi.nlm.nih.gov/pubmed/17728841 http://dx.doi.org/10.1155/2007/63234 |
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