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CTLA-4 blockade during dendritic cell based booster vaccination influences dendritic cell survival and CTL expansion
Dendritic cells (DCs) are potent antigen-presenting cells and critical for the priming of CD8+ T cells. Therefore the use of these cells as adjuvant cells has been tested in a large number of experimental and clinical vaccination studies, in particular cancer vaccine studies. A number of protocols a...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950502/ https://www.ncbi.nlm.nih.gov/pubmed/17662155 http://dx.doi.org/10.1186/1476-8518-5-9 |