Elk1 and SRF transcription factors convey basal transcription and mediate glucose response via their binding sites in the human LXRB gene promoter

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The nuclear receptors LXRα (NR1H3) and LXRβ (NR1H2) are attractive drug targets for the treatment of diabetes and cardiovascular disease due to their established role as regulators of cholesterol and lipid metabolism. A large body of literature has recently indicated their important roles in glucose...

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Detalles Bibliográficos
Autores principales: Nilsson, Maria, Dahlman-Wright, Karin, Karelmo, Charlotta, Gustafsson, Jan-Åke, Steffensen, Knut R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950530/
https://www.ncbi.nlm.nih.gov/pubmed/17626048
http://dx.doi.org/10.1093/nar/gkm492
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