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Novel activity of eukaryotic translocase, eEF2: dissociation of the 80S ribosome into subunits with ATP but not with GTP

Ribosomes must dissociate into subunits in order to begin protein biosynthesis. The enzymes that catalyze this fundamental process in eukaryotes remained unknown. Here, we demonstrate that eukaryotic translocase, eEF2, which catalyzes peptide elongation in the presence of GTP, dissociates yeast 80S...

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Detalles Bibliográficos
Autores principales: Demeshkina, Natalia, Hirokawa, Go, Kaji, Akira, Kaji, Hideko
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950535/
https://www.ncbi.nlm.nih.gov/pubmed/17586816
http://dx.doi.org/10.1093/nar/gkm468

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