Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline

We applied a computational pipeline based on comparative genomics to bacteria, and identified 22 novel candidate RNA motifs. We predicted six to be riboswitches, which are mRNA elements that regulate gene expression on binding a specific metabolite. In separate studies, we confirmed that two of thes...

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Detalles Bibliográficos
Autores principales: Weinberg, Zasha, Barrick, Jeffrey E., Yao, Zizhen, Roth, Adam, Kim, Jane N., Gore, Jeremy, Wang, Joy Xin, Lee, Elaine R., Block, Kirsten F., Sudarsan, Narasimhan, Neph, Shane, Tompa, Martin, Ruzzo, Walter L., Breaker, Ronald R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950547/
https://www.ncbi.nlm.nih.gov/pubmed/17621584
http://dx.doi.org/10.1093/nar/gkm487

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