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Enantioselectivity of human AMP, dTMP and UMP-CMP kinases

l-Nucleoside analogues such as lamivudine are active for treating viral infections. Like d-nucleosides, the biological activity of the l-enantiomers requires their stepwise phosphorylation by cellular or viral kinases to give the triphosphate. The enantioselectivity of NMP kinases has not been thoro...

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Detalles Bibliográficos
Autores principales:	Alexandre, Julie A.C., Roy, Béatrice, Topalis, Dimitri, Pochet, Sylvie, Périgaud, Christian, Deville-Bonne, Dominique
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950558/ https://www.ncbi.nlm.nih.gov/pubmed/17626051 http://dx.doi.org/10.1093/nar/gkm479

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