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Differential Requirements for MCM Proteins in DNA Replication in Drosophila S2 Cells

BACKGROUND: The MCM2-7 proteins are crucial components of the pre replication complex (preRC) in eukaryotes. Since they are significantly more abundant than other preRC components, we were interested in determining whether the entire cellular content was necessary for DNA replication in vivo. METHOD...

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Detalles Bibliográficos
Autores principales: Crevel, Gilles, Hashimoto, Reina, Vass, Sharron, Sherkow, Jake, Yamaguchi, Masamitsu, Heck, Margarete M.S., Cotterill, Sue
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950684/
https://www.ncbi.nlm.nih.gov/pubmed/17786205
http://dx.doi.org/10.1371/journal.pone.0000833