Phenotype-genotype analysis of CYP2C19 in Colombian mestizo individuals

BACKGROUND: Omeprazole is metabolized by the hepatic cytochrome P450 (CYP) 2C19 enzyme to 5-hydroxyomeprazole. CYP2C19 exhibits genetic polymorphisms responsible for the presence of poor metabolizers (PMs), intermediate metabolizers (IMs) and extensive metabolizers (EMs). The defective mutations of...

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Detalles Bibliográficos
Autores principales: Isaza, Carlos, Henao, Julieta, Martínez, José H Isaza, Arias, Juan C Sepúlveda, Beltrán, Leonardo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950696/
https://www.ncbi.nlm.nih.gov/pubmed/17623107
http://dx.doi.org/10.1186/1472-6904-7-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950696/
https://www.ncbi.nlm.nih.gov/pubmed/17623107
http://dx.doi.org/10.1186/1472-6904-7-6

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