Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation

BACKGROUND: Protein aggregation is a hallmark of several neurodegenerative diseases including Huntington's disease and Parkinson's disease. Proteins containing long, homopolymeric stretches of glutamine are especially prone to form aggregates. It has long been known that the small protein...

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Detalles Bibliográficos
Autores principales: Howard, Rebecca A, Sharma, Pratima, Hajjar, Connie, Caldwell, Kim A, Caldwell, Guy A, du Breuil, Rusla, Moore, Rhonda, Boyd, Lynn
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952058/
https://www.ncbi.nlm.nih.gov/pubmed/17663792
http://dx.doi.org/10.1186/1471-2121-8-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952058/
https://www.ncbi.nlm.nih.gov/pubmed/17663792
http://dx.doi.org/10.1186/1471-2121-8-32

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