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Polymorphisms within Novel Risk Loci for Type 2 Diabetes Determine β-Cell Function

BACKGROUND: Type 2 diabetes arises when insulin resistance-induced compensatory insulin secretion exhausts. Insulin resistance and/or β-cell dysfunction result from the interaction of environmental factors (high-caloric diet and reduced physical activity) with a predisposing polygenic background. Ve...

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Detalles Bibliográficos
Autores principales:	Staiger, Harald, Machicao, Fausto, Stefan, Norbert, Tschritter, Otto, Thamer, Claus, Kantartzis, Konstantinos, Schäfer, Silke A., Kirchhoff, Kerstin, Fritsche, Andreas, Häring, Hans-Ulrich
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952072/ https://www.ncbi.nlm.nih.gov/pubmed/17786204 http://dx.doi.org/10.1371/journal.pone.0000832

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