HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR

BACKGROUND: RNA interference (RNAi) is a regulatory mechanism conserved in higher eukaryotes. The RNAi pathway generates small interfering RNA (siRNA) or micro RNA (miRNA) from either long double stranded stretches of RNA or RNA hairpins, respectively. The siRNA or miRNA then guides an effector comp...

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Detalles Bibliográficos
Autores principales: Klase, Zachary, Kale, Prachee, Winograd, Rafael, Gupta, Madhur V, Heydarian, Mohammad, Berro, Reem, McCaffrey, Timothy, Kashanchi, Fatah
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955452/
https://www.ncbi.nlm.nih.gov/pubmed/17663774
http://dx.doi.org/10.1186/1471-2199-8-63

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