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An Amphioxus Gli Gene Reveals Conservation of Midline Patterning and the Evolution of Hedgehog Signalling Diversity in Chordates

BACKGROUND: Hedgehog signalling, interpreted in receiving cells by Gli transcription factors, plays a central role in the development of vertebrate and Drosophila embryos. Many aspects of the signalling pathway are conserved between these lineages, however vertebrates have diverged in at least one k...

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Detalles Bibliográficos
Autores principales: Shimeld, Sebastian M., van den Heuvel, Marcel, Dawber, Rebecca, Briscoe, James
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955834/
https://www.ncbi.nlm.nih.gov/pubmed/17848995
http://dx.doi.org/10.1371/journal.pone.0000864