Disruption of Retinoic Acid Receptor Alpha Reveals the Growth Promoter Face of Retinoic Acid

BACKGROUND: Retinoic acid (RA), the bioactive derivative of Vitamin A, by epigenetically controlling transcription through the RA-receptors (RARs), exerts a potent antiproliferative effect on human cells. However, a number of studies show that RA can also promote cell survival and growth. In the cou...

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Detalles Bibliográficos
Autores principales: Somenzi, Giulia, Sala, Giusy, Rossetti, Stefano, Ren, MingQiang, Ghidoni, Riccardo, Sacchi, Nicoletta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959242/
https://www.ncbi.nlm.nih.gov/pubmed/17786207
http://dx.doi.org/10.1371/journal.pone.0000836

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