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Early Loss of Xist RNA Expression and Inactive X Chromosome Associated Chromatin Modification in Developing Primordial Germ Cells
BACKGROUND: The inactive X chromosome characteristic of female somatic lineages is reactivated during development of the female germ cell lineage. In mouse, analysis of protein products of X-linked genes and/or transgenes located on the X chromosome has indicated that reactivation occurs after primo...
Autores principales: | de Napoles, Mariana, Nesterova, Tatyana, Brockdorff, Neil |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959243/ https://www.ncbi.nlm.nih.gov/pubmed/17848991 http://dx.doi.org/10.1371/journal.pone.0000860 |
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