Cargando…
Arterial Response to Shear Stress Critically Depends on Endothelial TRPV4 Expression
BACKGROUND: In blood vessels, the endothelium is a crucial signal transduction interface in control of vascular tone and blood pressure to ensure energy and oxygen supply according to the organs' needs. In response to vasoactive factors and to shear stress elicited by blood flow, the endotheliu...
Autores principales: | Hartmannsgruber, Veronika, Heyken, Willm-Thomas, Kacik, Michael, Kaistha, Anuradha, Grgic, Ivica, Harteneck, Christian, Liedtke, Wolfgang, Hoyer, Joachim, Köhler, Ralf |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959246/ https://www.ncbi.nlm.nih.gov/pubmed/17786199 http://dx.doi.org/10.1371/journal.pone.0000827 |
Ejemplares similares
-
NF-κB Pathway as a Potential Target for Treatment of Critical Stage COVID-19 Patients
por: Kircheis, Ralf, et al.
Publicado: (2020) -
TRPV4-mediated trigeminal pain: behavior assessments and mechanisms
por: Chen, Yong, et al.
Publicado: (2014) -
Piezo1 acts upstream of TRPV4 to induce pathological changes in endothelial cells due to shear stress
por: Swain, Sandip M., et al.
Publicado: (2020) -
Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias
por: Leddy, Holly A, et al.
Publicado: (2014) -
Modulation of K(Ca)3.1 Channels by Eicosanoids, Omega-3 Fatty Acids, and Molecular Determinants
por: Kacik, Michael, et al.
Publicado: (2014)