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Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report
BACKGROUND: Severe hypertriglyceridaemia (HTG) is uncommon but most prevalent in subjects with type 2 diabetes mellitus (T2DM) and excess ethanol intake. CASE PRESENTATION: We describe a case of a middle age male (53 y) presenting to the emergency room with acute atypical central chest pain and seve...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963453/ https://www.ncbi.nlm.nih.gov/pubmed/17629933 http://dx.doi.org/10.1186/1752-1947-1-51 |
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author | Albahrani, Ali I Usher J, Jannette Marks, Eileen Ranganath, L Shenkin, Alan |
author_facet | Albahrani, Ali I Usher J, Jannette Marks, Eileen Ranganath, L Shenkin, Alan |
author_sort | Albahrani, Ali I |
collection | PubMed |
description | BACKGROUND: Severe hypertriglyceridaemia (HTG) is uncommon but most prevalent in subjects with type 2 diabetes mellitus (T2DM) and excess ethanol intake. CASE PRESENTATION: We describe a case of a middle age male (53 y) presenting to the emergency room with acute atypical central chest pain and severe HTG in the absence of evidence of overt ischaemic heart disease (IHD). Admission ECG and EET (exercise tolerance test) were negative for reversible ischaemic changes. His admission glucose was 12.2 mmol/l, triglycerides (TG) were 103 mmol/l, total cholesterol 37 mmol/l. Cardiac Troponin T could not be measured on three occasions but CK MB mass was normal at 3 μg/l. The patient was started on Bezafibrate 400 mg OD, Simvastatin 20 mg nocte, Omacor (Omega-3 fish oil) 1 gm bd and Metformin 500 mg tds. Four weeks after admission, lipid and liver profiles showed remarkable improvement, TG 2.9 mmol/l, Tchol 6.3 mmol/l and HDLc 1.5 mmol/l, ALAT and GGT were normal. CONCLUSION: A case report of severe hypertriglyceridaemia with atypical presentation demonstrate the role of combined lipid modifying agents in lowering triglycerides and cholesterol as well as improving liver enzymes. |
format | Text |
id | pubmed-1963453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-19634532007-09-04 Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report Albahrani, Ali I Usher J, Jannette Marks, Eileen Ranganath, L Shenkin, Alan J Med Case Reports Case Report BACKGROUND: Severe hypertriglyceridaemia (HTG) is uncommon but most prevalent in subjects with type 2 diabetes mellitus (T2DM) and excess ethanol intake. CASE PRESENTATION: We describe a case of a middle age male (53 y) presenting to the emergency room with acute atypical central chest pain and severe HTG in the absence of evidence of overt ischaemic heart disease (IHD). Admission ECG and EET (exercise tolerance test) were negative for reversible ischaemic changes. His admission glucose was 12.2 mmol/l, triglycerides (TG) were 103 mmol/l, total cholesterol 37 mmol/l. Cardiac Troponin T could not be measured on three occasions but CK MB mass was normal at 3 μg/l. The patient was started on Bezafibrate 400 mg OD, Simvastatin 20 mg nocte, Omacor (Omega-3 fish oil) 1 gm bd and Metformin 500 mg tds. Four weeks after admission, lipid and liver profiles showed remarkable improvement, TG 2.9 mmol/l, Tchol 6.3 mmol/l and HDLc 1.5 mmol/l, ALAT and GGT were normal. CONCLUSION: A case report of severe hypertriglyceridaemia with atypical presentation demonstrate the role of combined lipid modifying agents in lowering triglycerides and cholesterol as well as improving liver enzymes. BioMed Central 2007-07-14 /pmc/articles/PMC1963453/ /pubmed/17629933 http://dx.doi.org/10.1186/1752-1947-1-51 Text en Copyright © 2007 Albahrani et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Albahrani, Ali I Usher J, Jannette Marks, Eileen Ranganath, L Shenkin, Alan Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report |
title | Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report |
title_full | Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report |
title_fullStr | Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report |
title_full_unstemmed | Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report |
title_short | Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report |
title_sort | atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963453/ https://www.ncbi.nlm.nih.gov/pubmed/17629933 http://dx.doi.org/10.1186/1752-1947-1-51 |
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