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Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes
PRC2 is thought to be the histone methyltransferase (HMTase) responsible for H3-K27 trimethylation at Polycomb target genes. Here we report the biochemical purification and characterization of a distinct form of Drosophila PRC2 that contains the Polycomb group protein polycomblike (Pcl). Like PRC2,...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964751/ https://www.ncbi.nlm.nih.gov/pubmed/17762866 http://dx.doi.org/10.1038/sj.emboj.7601837 |