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Gain-of-Function R225W Mutation in Human AMPKγ(3) Causing Increased Glycogen and Decreased Triglyceride in Skeletal Muscle

BACKGROUND: AMP-activated protein kinase (AMPK) is a heterotrimeric enzyme that is evolutionarily conserved from yeast to mammals and functions to maintain cellular and whole body energy homeostasis. Studies in experimental animals demonstrate that activation of AMPK in skeletal muscle protects agai...

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Detalles Bibliográficos
Autores principales:	Costford, Sheila R., Kavaslar, Nihan, Ahituv, Nadav, Chaudhry, Shehla N., Schackwitz, Wendy S., Dent, Robert, Pennacchio, Len A., McPherson, Ruth, Harper, Mary-Ellen
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964808/ https://www.ncbi.nlm.nih.gov/pubmed/17878938 http://dx.doi.org/10.1371/journal.pone.0000903

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