DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons

The role of DNA cytosine methylation, an epigenetic regulator of chromatin structure and function, during normal and pathological brain development and aging remains unclear. Here, we examined by MethyLight PCR the DNA methylation status at 50 loci, encompassing primarily 5′ CpG islands of genes rel...

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Detalles Bibliográficos
Autores principales: Siegmund, Kimberly D., Connor, Caroline M., Campan, Mihaela, Long, Tiffany I., Weisenberger, Daniel J., Biniszkiewicz, Detlev, Jaenisch, Rudolf, Laird, Peter W., Akbarian, Schahram
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964879/
https://www.ncbi.nlm.nih.gov/pubmed/17878930
http://dx.doi.org/10.1371/journal.pone.0000895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964879/
https://www.ncbi.nlm.nih.gov/pubmed/17878930
http://dx.doi.org/10.1371/journal.pone.0000895

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