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Assessment of post-laparotomy pain in laboratory mice by telemetric recording of heart rate and heart rate variability
BACKGROUND: Pain of mild to moderate grade is difficult to detect in laboratory mice because mice are prey animals that attempt to elude predators or man by hiding signs of weakness, injury or pain. In this study, we investigated the use of telemetry to identify indicators of mild-to-moderate post-l...
Autores principales: | Arras, Margarete, Rettich, Andreas, Cinelli, Paolo, Kasermann, Hans P, Burki, Kurt |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1965463/ https://www.ncbi.nlm.nih.gov/pubmed/17683523 http://dx.doi.org/10.1186/1746-6148-3-16 |
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