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In silico, biologically-inspired modelling of genomic variation generation in surface proteins of Trypanosoma cruzi

BACKGROUND: Protozoan parasites improve the likelihood of invading or adapting to the host through their capacity to present a large repertoire of surface molecules. The understanding of the mechanisms underlying the generation of antigenic diversity is crucial to aid in the development of therapies...

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Detalles Bibliográficos
Autores principales: Azuaje, Francisco J, Ramirez, Jose L, Da Silveira, Jose F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1965468/
https://www.ncbi.nlm.nih.gov/pubmed/17623100
http://dx.doi.org/10.1186/1475-9292-6-6